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For the latest Slicer documentation, visit the 4.10 page.

Introduction and Acknowledgements

This work was partially funded by CAPES and CNPq, a Brazillian Agencies. Information on CAPES can be obtained on the CAPES website and CNPq website.
Author: Antonio Carlos da S. Senra Filho, CSIM Laboratory (University of Sao Paulo, Department of Computing and Mathematics)
Contact: Antonio Carlos da S. Senra Filho <email></email>

CSIM Laboratory  
University of Sao Paulo  
CNPq Brazil  
CAPES Brazil  

Extension Description


Brain tissue segmentation plays an important role in many different image processing steps, which offers a possibility to study different neurodegenerative diseases or also in more specific tasks such as in brain structural quantitative morphological parameters such as brain atrophy. For this reason, brain tissue segmentation procedures have been intensively studied in recent years. This extension aims to offer a fast, robust and simple solutions for brain tissue segmentation, in which specific segmentation tasks are separated into different modules. See the modules list below to find the most appropriate tool for your study.


NOTE: The Brain Structures Segmenter is the main module for a general brain segmentation approach, which uses a predefined image processing pipeline in order to result in a smoothed tissue mask. See the module's documentation for more details.

Each segmentation approach is related to a specific algorithm, which is explained in more details in the pulications placed in References section. Please, cite the proper algorithm if any of these methods were used in a scientific study.

Use Cases

Most frequently used for these scenarios:

  • Use Case 1: Tissue classification
    • There are several image quantitative approaches that are applied only in a certain tissue type (for instance, cortical thickness) in which a previous brain segmentation could be needed.
  • Use Case 2: Restrict brain regions for image quantitative analysis
    • A white matter mask could be used for specific measurements in some brain diseases, for example, in Multiple Sclerosis it could be useful to help lesion detection algorithms.

Similar Extensions

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  • [k-Means]
  • [BLS paper]

Information for Developers