Documentation/4.4/Modules/GelDosimetry

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For the latest Slicer documentation, visit the 4.10 page.

Cancer Care Ontario SparKit SparKit

Introduction and Acknowledgements

Authors: Jennifer Andrea (PerkLab, Queen's University), Csaba Pinter (PerkLab, Queen's University), Mattea Welch (University of Toronto)
Contributors: Kevin Alexander (Kingston General Hospital), John Schreiner (Kingston General Hospital)
Contacts:

License: Slicer license
Download/install: install 3D Slicer, start 3D Slicer, open the Extension Manager, install SlicerRT extension, restart, install the GelDosimetry extension

Extension Description

GelDosimetry Logo 128x128.png

  • Gel dosimetry analysis is a tool used in commissioning new radiation techniques and to validate the accuracy of radiation treatment by enabling visual comparison of the planned dose to the delivered dose, where correspondence between the two dose distributions is achieved using embedded landmarks. Gel dosimetry is based on imaging chemical systems spatially fixed in gelatin, which exhibit a detectable change upon irradiation. This chemical change is related to the amount of radiation received and can be probed by several imaging techniques, allowing 3D dose information to be obtained.
  • The slicelet currently supports CT-optCT clinical dosimetry workflows, with MR-MR preclinical and others coming up. Please contact us if you have a similar workflow you'd like to see supported
  • The extension depends on the SlicerRT general radiation therapy extension

Use Cases

  • Gel dosimetry analysis workflow:
    1. Loading planning image (PLANCT) and a planned dose distribution (PLANDOSE)
    2. Load an on-board imager cone beam CT scan (OBI)
    3. Register it to PLANCT
    4. Transform PLANDOSE using result transform (to OBI coordinate frame)
    5. Load 3D optical CT scan of the gel, or a 2D scan of the film. (MEASURED)
    6. Register MEASURED to OBI using fiducial marks, using rigid transform
    7. Transform MEASURED using result transform (to OBI coordinate frame)
    8. Load Percent Depth Dose data (two-column spreadsheet)
    9. Load experimental CALIBRATION 3D optical CT scan from VFF file
    10. Get mean optical densities from the central cylinder of the CALIBRATION volume
    11. Align PDD curve with the curve resulting from step 10
    12. Calibrate PDD data using RDF and electron MU values input by the user
    13. Fit polynomial on the optical density vs. dose curve (resulting from the aligned calibration curves)
    14. Perform a gamma, chi, etc. test between MEASURED and PLANDOSE, yielding another 3D volume COMPARISON
    15. Extract statistics from COMPARISON
Gel dosimetry data flow diagram

Gel dosimetry screenshot

Pdd aligment curve screenshot
Calibration curve screenshot

Tutorials

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Similar Extensions

  • SlicerRT: GelDosimetry uses several modules from the SlicerRT extension

References

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Information for Developers

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