EMSegmenter-Tasks

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What is a task?

Most clinicians are using the EMSegmenter to segment specific parts of the human body. Those segmentations depend heavily on the used input data. The signal level in the input data varies with the used image modalities (e.g. MRI, CT, ...) and with each anatomical structure. The EMSegmenter can take advantage of some knowledge about the signal level of those anatomical structures in the different image modalities.
Technically, each tasks consist of a .mrml file and a .tcl file.
The .mrml file stores the anatomical properties (mean values, covariance values) in a user defined tree structure.
The .tcl script is used to perform some pre-processing on the input data.

Visit the following web page to create your own task or we can help you .

Segmentation Task Library

Existing Tasks in Slicer 3.6.3

Tasks for Slicer 3.6.4

Tasks in development

External Command Lines (Under Development)

Additional Use Cases

Quantitative assessment using MPRAGE and Flair images

  • Collaborator: Tammie Benzinger , Washington University School of Medicine
  • Short description: Quantitative assessment using MPRAGE and Flair images
  • Image specification: Dimension: 256x256x160 , Spacing 1x1x1, T2 MPRAGE
  • Used Task: MRI Human Brain Experimental (with skull stripping)

Brain Atrophy in Aging Patients

  • Collaborator: David Tate, PI (Brigham and Women's Hospital), Daniel McCaffrey (Brigham and Women's Hospital), Alex Zaitsev (Brigham and Women's Hospital/Surgical Planning Laboratory) and Jewish Hospital
  • Short description: Evaluate Brain Atrophy in aging subjects (NOTE: the segmentation was done for old scans from 90s. No other tools could segment CSF.)
  • Image specification: NA Tesla, Scanner: NA, Psuedo T1, Axial Scans, TR/TI/TE=NA, pixel_xsize = 0.937500, pixel_ysize = 0.937500, fov = 240.000000, aspect = 0.000000, thick = 5.000000
  • Used Task: MRI Human Brain

Brain Atrophy in HIV Patients

  • Collaborator: David Tate, PI (Brigham and Women's Hospital), Troy Russel (Brigham and Women's Hospital), Alex Zaitsev (Brigham and Women's Hospital/Surgical Planning Laboratory) and National HIV Consortium
  • Short description: Evaluate Brain Atrophy in HIV Patients
  • Image specification: 3 Tesla, Scanner: NA, MPRAGE, Sagittal Scans, TR/TI/TE=NA, pixel_xsize = 0.9375, pixel_ysize = 0.9375, fov = NA, aspect = NA, space = 1.5
  • Used Task: MRI Human Brain

Pediatric MS Study

  • Collaborator: Tanuja Chitnis PI (Brigham and Women's Hospital/Multiple Sclerosis Center), Alexander Zaitsev (Brigham and Women's Hospital/Surgical Planning Laboratory) and Massachusetts General Hospital
  • Short description: Evaluate brain atrophy for pediatric MS Patients
  • Image specification: 3 Tesla, Scanner: SIGNA HDx / GE MEDICAL SYSTEMS, 3D MPRAGE, Sagital Scans, TR/TI/TE=24/0/7 ms, pixel_xsize = 0.976600, pixel_ysize = 0.976600, fov = 250.009598, aspect = 1.535941, thick = 1.500000, space = 0.000000
  • Used Task: MRI Human Brain

Social Cognition Study

  • Collaborator: Collaborator: Andrea Mike, MD (Pecs University, Hungary), Charles Guttmann, MD, Alexander Zaitsev (Brigham and Women's Hospital)
  • Short description: Evaluate brain atrophy for elderly MS patients.
  • Number of processed cases: 50
  • Image specification: 3 Tesla, Scanner: Magnetom TIM Trio, Siemens, 3D MPRAGE, Slice thickness: 1.2mm, Spacing 1.2 1 1 (mm)
  • Used Task: MRI Human Brain

Physiological Brain Activity Longitudinal Study

  • Collaborator: Laura Horky PI (Brigham and Women's Hospital(BWH)), Jon Hainer (BWH), Wendy Plesniak (BWH), Alexander Zaitsev (BWH), Ron Kikinis (BWH) and BWH Division of Nuclear Medicine
  • Short description: Evaluate glycolitical brain activity in CSF and White Matter for the patients undergoing chemical therapy courses.
  • Image specification: 1.5 Tesla ,Scanner: SIGNA EXCITE / GE MEDICAL SYSTEMS, T1, Axial Scans, TR/TI/TE=500/0/21 ms, pixel_xsize = 0.781251, pixel_ysize = 0.781244, fov = 0.000000, aspect = 7.679990, thick = 5.000000, space = 1.000000
  • Used Task: MRI Human Brain Hemisphere

Comprehensive Longitudinal Investigation of Multiple Sclerosis at Brigham and Women’s Hospital (CLIMB) Study

  • CLIMB Study Web Page
  • Collaborator: Svetlana Egorova MD/PhD (Brigham and Women's Hospital(BWH)), Alexander Zaitsev PhD (BWH)
  • Short description: Provide Basic EM Segmentation for estimation of brain parenchymal fraction (BPF) . The processing is being performed for the cases with failing PD TDS+ segmentation. The T1-type scans are segmented and registered to PD/T2 images. The requests are being submitted over the Web GUI.
  • Image specification: 1.5 Tesla ,Scanner: Varies among participants.
  • Used Task: MRI Human Brain Hemisphere