Difference between revisions of "Slicer3:UIDesign:WorkingProblems:BCAnalysis:Volumetric"

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** Percent change
 
** Percent change
 
** Absolute change  
 
** Absolute change  
** '''Question:''' units for these values -- mm^2?
+
** '''Question:''' units for these values -- mm!
  
 
== Volume Measurements Workflow ==
 
== Volume Measurements Workflow ==

Revision as of 13:14, 6 August 2009

Home < Slicer3:UIDesign:WorkingProblems:BCAnalysis:Volumetric

Back to Project Overview

Volumetric Tumor Analysis for Breast Cancer

Goal

Goal is to accommodate basic RECIST assessment for breast cancer (Response Evaluation Criteria In Solid Tumors). (RECIST is a set of published rules that define when cancer patients improve ("respond"), stay the same ("stable") or worsen ("progression") during treatments).

  • Determine features that currently exist in Slicer
  • Develop features that don't
  • Provide a framework that knits features together in a comfortable workflow.

Linear Measurements Workflow

  • Scroll through baseline
  • Find the tumor's longest diameter (no reformat, just on orig acquisition)
  • Measure the longest diameter D1(t1)
  • Measure the orthogonal diameter D2(t1)
  • If there are multiple tumors, measure both diams in each tumor and sum to get relative D1(t1) and relative D2(t1)
  • Perform same measurements D1(t2) and D2(t2)
  • Specific results to report:
    • Percent change
    • Absolute change
    • Question: units for these values -- mm!

Volume Measurements Workflow

  • Scroll through dataset and determine tumor with largest diameter.
  • Segment largest diameter tumor in baseline Question: multiple tumors ok?
    • Manual or automatic segmentation OK
  • Segment tumor in followup Questions: Must be same tumor, or largest diameter in followup? multiple tumors ok?
    • Manual or automatic segmentation OK -- but use same method
  • Measure:
    • Volume(t1) and Volume(t2) Question: which is preferred, mm^3 or cc?
    • Relative % difference
    • Absolute change (same units as above)