Difference between revisions of "Documentation/Nightly/Extensions/LesionSimulator"

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Image:LesionLoad_2mL.png|
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Image:LesionLoad_2mL.png|MS lesion simulation with 2mL lesion load
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Image:LesionLoad_5mL.png|
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Image:LesionLoad_5mL.png|MS lesion simulation with 5mL lesion load
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Image:LesionLoad_40mL.png|MS lesion simulation with 40mL lesion load
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Image:3DLesionsOverlay.png|A 3D reconstruction of 2mL, 5mL and 40mL lesion loads showing that each lesion pattern is independent of each other
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Image:MNI152_orig.png|T1 weighted MRI brain in axial orientation (provided by the ICBM-MNI152 non linear brain template)
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Image:MNI152_lesionload40mL.png|The same MNI152 template with 40mL lesion load simulated lesions (axial orientation)
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Image:MNI152_orig_sag.png|T1 weighted MRI brain in sagittal orientation (provided by the ICBM-MNI152 non linear brain template)
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Image:MNI152_lesionload40mL_sag.png|The same MNI152 template with 40mL lesion load simulated lesions (sagittal orientation)
 
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Revision as of 19:24, 12 December 2016

Home < Documentation < Nightly < Extensions < LesionSimulator


For the latest Slicer documentation, visit the read-the-docs.


Introduction and Acknowledgements

This work was partially funded by CAPES and CNPq, a Brazillian Agencies. Information on CAPES can be obtained on the CAPES website and CNPq website.
Author: Antonio Carlos da S. Senra Filho, CSIM Laboratory (University of Sao Paulo, Department of Computing and Mathematics)
Contact: Antonio Carlos da S. Senra Filho <email>acsenrafilho@usp.br</email>

CSIM Laboratory  
University of Sao Paulo  
CNPq Brazil  
CAPES Brazil  


Extension Description

LesionSimulator-logo.png

This extension offer a set of tools for brain lesion simulation, based on MRI images. At moment, the module MS Lesion Simulator is available, where it can simulates both baseline scan lesion volumes (given a lesion load) and longitudinal image simulations. The general procedure describe in the MS Lesion Simulator is described in the original paper.


Modules

Use Cases

Most frequently used for these scenarios:

  • Use Case 1: Simulate different anatomical/clinical MS lesions patterns on healthy individuals MRI images
    • In the baseline scan approach, it is offered a simulation procedure where a determined lesion load is reconstructed using a subject specific anatomical features, resulting in a realistic MS lesion load simulation.
  • Use Case 2: Simulate longitudinal MS lesion progression on clinical healthy individuals MRI images

  • MS lesion simulation with 2mL lesion load

  • MS lesion simulation with 5mL lesion load

  • MS lesion simulation with 40mL lesion load

  • A 3D reconstruction of 2mL, 5mL and 40mL lesion loads showing that each lesion pattern is independent of each other

  • T1 weighted MRI brain in axial orientation (provided by the ICBM-MNI152 non linear brain template)

  • The same MNI152 template with 40mL lesion load simulated lesions (axial orientation)

  • T1 weighted MRI brain in sagittal orientation (provided by the ICBM-MNI152 non linear brain template)

  • The same MNI152 template with 40mL lesion load simulated lesions (sagittal orientation)

Similar Extensions

N/A

References

  • paper

Information for Developers

Work in progress
 Section under construction.


Repositories:

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