# Documentation/4.6/Modules/ACPCTransform

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# Introduction and Acknowledgements

Title: ACPC Transform
Author(s)/Contributor(s): Nicole Aucoin (SPL, BWH), Ron Kikinis (SPL, BWH)
Acknowledgements: This work is part of the National Alliance for Medical Image Computing (NAMIC), funded by the National Institutes of Health through the NIH Roadmap for Medical Research, Grant U54 EB005149.
Contact: Nicole Aucoin, <email>nicole@bwh.harvard.edu</email>

Information on NA-MIC can be obtained from the NA-MIC website.

 Surgical Planning Laboratory (SPL)
 National Alliance for Medical Image Computing (NA-MIC)
 Neuroimage Analysis Center (NAC)

# Module Description

Calculate a transformation from two lists of fiducial points.

The ACPC line extends between two points, one at the anterior commissure and one at the posterior commissure. The resulting transform will bring the line connecting the two points horizontal to the AP axis.

The midline is a series of points defining the division between the hemispheres of the brain (the mid sagittal plane). The resulting transform will result in the output volume having the mid sagittal plane lined up with the AS plane.

Use the Filtering module Resample Scalar/Vector/DWI Volume to apply the transformation to a volume.

# Use Cases

Most frequently used for these scenarios:

• Use Case 1: to align brain volumes.

# Panels and their use

Parameters:

• Transform panel: Calculate a transform from midline and ACPC fiducial lists.
• ACPC Line (ACPC): ACPC line, a list of two fiducial points, one at the anterior commissure and one at the posterior commissure.
• Midline (Midline): The midline is a series of points defining the division between the hemispheres of the brain (the mid sagittal plane).
• Output transform (OutputTransform): A transform filled in from the ACPC and Midline registration calculation.
• Debug pane:
• Debug (debugSwitch): Click this checkbox to see debugging output.

List of parameters generated transforming this XML file using this XSL file. To update the URL of the XML file, edit this page.

# Similar Modules

• Other registration modules can align volumes using different methods.