# Documentation/4.1/Modules/ACPCTransform

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# Introduction and Acknowledgements

This work is part of the National Alliance for Medical Image Computing (NA-MIC), funded by the National Institutes of Health through the NIH Roadmap for Medical Research, Grant U54 EB005149. Information on NA-MIC can be obtained from the NA-MIC website.
Author: Nicole Aucoin, BWH
Contributor: Ron Kikinis, BWH
Contact: Nicole Aucoin, <email>nicole@bwh.harvard.edu</email>

 Surgical Planning Laboratory (SPL)
 National Alliance for Medical Image Computing (NA-MIC)
 Neuroimage Analysis Center (NAC)

# Module Description

Calculate a transformation from two lists of fiducial points.

ACPC line is two fiducial points, one at the anterior commissure and one at the posterior commissure. The resulting transform will bring the line connecting them to horizontal to the AP axis.

The midline is a series of points defining the division between the hemispheres of the brain (the mid sagittal plane). The resulting transform will put the output volume with the mid sagittal plane lined up with the AS plane.

Use the Filtering moduleResample Scalar/Vector/DWI Volumeto apply the transformation to a volume.

# Use Cases

Most frequently used for these scenarios:

• Use Case 1: to align two brain volumes.

# Panels and their use

A list of all the panels in the interface, their features, what they mean, and how to use them.

Parameters:

• Transform
• ACPC Line: ACPC line, two fiducial points, one at the anterior commissure and one at the posterior commissure.
• Midline: The midline is a series of points defining the division between the hemispheres of the brain (the mid sagittal plane).
• Output transform: A transform filled in from the ACPC and Midline registration calculation
• Debug
• Debug: Click if wish to see debugging output

# Similar Modules

• Other registration modules can align volumes using different methods.