Difference between revisions of "Documentation/4.0/Modules/IntensityDifferenceMetric"

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* the images are aligned and the major source of difference is due to the anatomical changes of the structures
 
* the images are aligned and the major source of difference is due to the anatomical changes of the structures
 
* the changes are small
 
* the changes are small
|[[Image:Slicer4_IntensityDifferenceMetric.png|thumb|450px|IntensityDifferenceMetric change quantification results]]
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* the structure of interest is hyperintensive in the baseline volume, and its segmentation is available
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|[[Image:Slicer4_IntensityDifferenceMetric.png|thumb|450px|Left to right: (1) baseline volume with the outline of the structure of interest; (2) followup volume co-registered with the baseline, with the same outline; (3) baseline volume with the voxels categorized as ''growth'' highlighted in red.]]
 
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Most frequently used for these scenarios:
 
Most frequently used for these scenarios:
 
* This metric is used in the last step of processing by [[Documentation/4.0/Modules/ChangeTracker|ChangeTracker]].
 
* This metric is used in the last step of processing by [[Documentation/4.0/Modules/ChangeTracker|ChangeTracker]].
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* The metric can be used on its own, as long as the assumptions listed above are considered.
  
 
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Revision as of 02:15, 24 November 2011

Home < Documentation < 4.0 < Modules < IntensityDifferenceMetric


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Introduction and Acknowledgements

This work is supported by NA-MIC, NAC, NCIGT, and the Slicer Community. This work is partially supported by Brain Science Foundation and NIH U01 CA151261.
Author: Andrey Fedorov, Kilian Pohl, Peter Black, Ron Kikinis, SPL
Contact: Andrey Fedorov <email>fedorov@bwh.harvard.edu</email>

NA-MIC  
Brain Science Foundation  
NCIGT  


Module Description

Intensity Difference Metric can be used to quantify the differences between the two images. The assumptions made by this metric are that:

  • the images are aligned and the major source of difference is due to the anatomical changes of the structures
  • the changes are small
  • the structure of interest is hyperintensive in the baseline volume, and its segmentation is available
Left to right: (1) baseline volume with the outline of the structure of interest; (2) followup volume co-registered with the baseline, with the same outline; (3) baseline volume with the voxels categorized as growth highlighted in red.


Use Cases

Most frequently used for these scenarios:

  • This metric is used in the last step of processing by ChangeTracker.
  • The metric can be used on its own, as long as the assumptions listed above are considered.

Tutorials

See ChangeTracker documentation.

Panels and their use

IntensityDifferenceMetric parameters panel


Similar Modules

References

  • Konukoglu, E., Wells, W. M., Novellas, S., Ayache, N., Kikinis, R., Black, P. M., & Pohl, K. M. (2008). Monitoring slowly evolving tumors. 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (pp. 812-815). IEEE. doi:10.1109/ISBI.2008.4541120 URL
  • Pohl, K. M., Konukoglu, E., Novellas, S., Ayache, N., Fedorov, A., Talos, I.-F., Golby, A., et al. (2011). A new metric for detecting change in slowly evolving brain tumors: validation in meningioma patients. Neurosurgery, 68(1 Suppl Operative), 225-33. doi:10.1227/NEU.0b013e31820783d5 URL

Information for Developers