Difference between revisions of "Slicer3:UIDesign:WorkingProblems:BCAnalysis:PET"
From Slicer Wiki
(Created page with 'Back to Project Overview = SUV Analysis for Breast Cancer =') |
|||
| Line 2: | Line 2: | ||
= SUV Analysis for Breast Cancer = | = SUV Analysis for Breast Cancer = | ||
| + | |||
| + | == Goal== | ||
| + | |||
| + | Goal is to accommodate basic RECIST assessment for breast cancer (Response Evaluation Criteria In Solid Tumors). (RECIST is a set of published rules that define when cancer patients improve ("respond"), stay the same ("stable") or worsen ("progression") during treatments). | ||
| + | |||
| + | * Determine features that currently exist in Slicer | ||
| + | * Develop features that don't | ||
| + | * Provide a framework that knits features together in a comfortable workflow. | ||
| + | |||
| + | == PET SUV Analysis Workflow == | ||
| + | |||
| + | * Segment the tumor by hand (ROI or VOI, can be simple circle or ellipsoid) | ||
| + | * Compute SUV of '''baseline''' | ||
| + | ** extract parameters from dicom header including | ||
| + | *** concentration | ||
| + | *** injected activity | ||
| + | *** patient weight | ||
| + | ** SUV = ( concentration (microcuries/cc) / injected activity (microcuries) ) - (patient weight (g)) | ||
| + | ** use maximum value | ||
| + | * Normalize ROI by SUVmax | ||
| + | * Compute SUV of '''followup''' | ||
| + | ** extract parameters from dicom header including | ||
| + | *** concentration | ||
| + | *** injected activity | ||
| + | *** patient weight | ||
| + | ** SUV = ( concentration (microcuries/cc) / injected activity (microcuries) ) - (patient weight (g)) | ||
| + | ** use maximum value | ||
| + | * Normalize ROI by SUVmax | ||
| + | * Resport parameters of interest | ||
| + | ** SUVmax_baseline, | ||
| + | ** SUVmax_followup, | ||
| + | ** % change | ||
| + | * For multiple tumors, report | ||
| + | ** sum of SUV_baselines | ||
| + | ** sum of SUV_followup | ||
| + | ** percent change | ||
Revision as of 11:37, 6 August 2009
Home < Slicer3:UIDesign:WorkingProblems:BCAnalysis:PETBack to Project Overview
SUV Analysis for Breast Cancer
Goal
Goal is to accommodate basic RECIST assessment for breast cancer (Response Evaluation Criteria In Solid Tumors). (RECIST is a set of published rules that define when cancer patients improve ("respond"), stay the same ("stable") or worsen ("progression") during treatments).
- Determine features that currently exist in Slicer
- Develop features that don't
- Provide a framework that knits features together in a comfortable workflow.
PET SUV Analysis Workflow
- Segment the tumor by hand (ROI or VOI, can be simple circle or ellipsoid)
- Compute SUV of baseline
- extract parameters from dicom header including
- concentration
- injected activity
- patient weight
- SUV = ( concentration (microcuries/cc) / injected activity (microcuries) ) - (patient weight (g))
- use maximum value
- extract parameters from dicom header including
- Normalize ROI by SUVmax
- Compute SUV of followup
- extract parameters from dicom header including
- concentration
- injected activity
- patient weight
- SUV = ( concentration (microcuries/cc) / injected activity (microcuries) ) - (patient weight (g))
- use maximum value
- extract parameters from dicom header including
- Normalize ROI by SUVmax
- Resport parameters of interest
- SUVmax_baseline,
- SUVmax_followup,
- % change
- For multiple tumors, report
- sum of SUV_baselines
- sum of SUV_followup
- percent change
