Documentation/Nightly/Modules/PkModeling - Revision history

Fedorov at 17:43, 21 November 2019

2019-11-21T17:43:42Z

Fedorov at 21:47, 20 November 2019

2019-11-20T21:47:36Z

Fedorov at 21:44, 20 November 2019

2019-11-20T21:44:03Z

Lasso at 20:08, 20 November 2019

2019-11-20T20:08:05Z

Fedorov at 20:10, 7 January 2016

2016-01-07T20:10:40Z

Fedorov at 20:08, 7 January 2016

2016-01-07T20:08:25Z

Stevedaxiao at 21:26, 4 January 2016

2016-01-04T21:26:29Z

Fedorov at 15:20, 19 August 2014

2014-08-19T15:20:34Z

Fedorov at 16:40, 24 July 2014

2014-07-24T16:40:35Z

Fedorov at 15:25, 11 June 2014

2014-06-11T15:25:44Z

← Older revision		Revision as of 17:43, 21 November 2019
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		+	* "Exploration and Study of MultiVolume Image Data using 3D Slicer" by Meysam Torabi, Brigham and Women's Hospital: https://github.com/QIICR/PkModeling/files/3875977/MultiVolumeExplorer_Meysam_SNR-April2013-v4.pdf
	* "3D Slicer for DCE-MRI Image Analysis" by Madeline Carr, University of Wollongong Australia: https://github.com/QIICR/PkModeling/files/3870911/DCE.and.3D.Slicer.Tutorial.pdf		* "3D Slicer for DCE-MRI Image Analysis" by Madeline Carr, University of Wollongong Australia: https://github.com/QIICR/PkModeling/files/3870911/DCE.and.3D.Slicer.Tutorial.pdf

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-* test
+* "3D Slicer for DCE-MRI Image Analysis" by Madeline Carr, University of Wollongong Australia: https://github.com/QIICR/PkModeling/files/3870911/DCE.and.3D.Slicer.Tutorial.pdf
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← Older revision		Revision as of 20:08, 20 November 2019
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 </pre>
-''Auto generated documentation of the parameters''
+'''Auto generated documentation of the parameters'''
 {{documentation/{{documentation/version}}/module-parametersdescription}}

← Older revision		Revision as of 20:08, 7 January 2016
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		+	''Auto generated documentation of the parameters''
		+	{{documentation/{{documentation/version}}/module-parametersdescription}}

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 * '''IO'''
 ** '''Input 4D Image''': 4D DCE-MRI data
 ** '''AIF Mask Image''': Mask designating the location of the arterial input function (AIF). AIF can either be calculated from the input using the aifMask, prescribed directly in concentration units using the prescribedAIF option, or via a population AIF.
 ** '''Prescribed AIF''': Prescribed arterial input function (AIF). AIF can either be calculated from the input using the aifMask option, via a population AIF, or can be prescribed directly in concentration units using the prescribedAIF option. An example of how a prescribed AIF can be defined is in [[File:AIF_example.mcsv.zip|this example .mcsv file]] (unzip before importing into Slicer!). Note that the x column corresponds to timestamps in seconds, and the y column is the contrast agent concentration (NOT image signal intensity).
@@ Line 76: / Line 77: @@
 ** '''Output AUC image''': area under the curve in the first 90 seconds
 * '''Advanced options''':
 ** '''Output R-squared goodness of fit image''': each pixel will be initialized to a value between 0 and 1 characterizing the goodness of fit. Larger values correspond to a better fit (see [http://en.wikipedia.org/wiki/Coefficient_of_determination R^2 measure description])
 ** '''Output Bolus Arrival Time Image''':  the bolus arrival time calculated at each pixel

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 ** '''AIF Mask Image''': Mask designating the location of the arterial input function (AIF). AIF can either be calculated from the input using the aifMask, prescribed directly in concentration units using the prescribedAIF option, or via a population AIF.
 ** '''Prescribed AIF''': Prescribed arterial input function (AIF). AIF can either be calculated from the input using the aifMask option, via a population AIF, or can be prescribed directly in concentration units using the prescribedAIF option. An example of how a prescribed AIF can be defined is in [[File:AIF_example.mcsv.zip|this example .mcsv file]] (unzip before importing into Slicer!). Note that the x column corresponds to timestamps in seconds, and the y column is the contrast agent concentration (NOT image signal intensity).
-** '''Output Ktrans image'''
+** '''Output Ktrans image''': volume transfer constant between blood plasma and extravascular extracellular space (EES) (min^-1)
-** '''Output ve image'''
+** '''Output ve image''': volume of EES per unit volume of tissue
-** '''Output fpv image'''
+** '''Output fpv image''': (or v_p) blood plasma volume per unit of tissue
-** '''Output maximum slope image'''
+** '''Output maximum slope image''': maximum slope of the signal intensity curve between any two consecutive timepoints
-** '''Output AUC image'''
+** '''Output AUC image''': area under the curve in the first 90 seconds
 * '''Advanced options''':
 ** '''Output R-squared goodness of fit image''': each pixel will be initialized to a value between 0 and 1 characterizing the goodness of fit. Larger values correspond to a better fit (see [http://en.wikipedia.org/wiki/Coefficient_of_determination R^2 measure description])

@@ Line 45: / Line 45: @@
 |[[Image:BC1_DCE.png|thumb|340px|Sample frame from a breast DCE MRI dataset (one of the datasets presented in a study by Huang et al. [6]]]
 |[[Image:BC1_Ktrans_map_ROI.png|thumb|340px|Ktrans map result of PK modeling using population AIF (Parker et al., [5])]]
 |}