Documentation/Nightly/Modules/EpileptogenicFocusDetection - Revision history

Gcarbajal at 22:09, 5 November 2015

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-Aguerrebere C, Sprechmann P, Musé P, Ferrando R. A-contrario localization of epileptogenic zones in SPECT images. Available :http://www.biomedicalimaging.org/2009/Papers/viewpapers.asp?papernum=1240 <br>
+Aguerrebere C, Sprechmann P, Musé P, Ferrando R. A-contrario localization of epileptogenic zones in SPECT images. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009. ISBI '09 <br>
 Ferrando R, Aguerrebere C, Albin G, Fernández A, Gómez A, Miceli F, Mottini A, Musé P, Nuñez M, Sprechmann P. Localization of epiloptogenic zones in SPECT images using an A-Contrario based algorithm. Evaluation with virtual phantoms and patients. Journal of Nuclear Medicine. 2010;51(suppl):494 <br>
 Mottini A, Miceli F, Albin G, Nuñez M, Ferrando R, Aguerrebere C, Fernández A. Integrated software for the detection of epileptogenic zones in refractory epilepsy. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:5700-3 <br>

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+Aguerrebere C, Sprechmann P, Musé P, Ferrando R. A-contrario localization of epileptogenic zones in SPECT images. Available :http://www.biomedicalimaging.org/2009/Papers/viewpapers.asp?papernum=1240 <br>
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 ** SPECT basal/SPECT ictal mask (intersection) computation
 * Foci detection: Differential (SISCOM) and a-contrario methods are implemented. Results can be visualized in MRI Space (if available) or SPECT Space. Results can be compared.
-** Differential method: Given two SPECT images (basal and ictal) in the same space (already registered), the images are substracted. An intensity normalization step is applied.
+** Differential method: The most used technique for detecting the epileptogenic zone(EZ) is to threshold the co-registered and normalized subtraction of these two images. This method has proven to be very useful but has the disadvantage that the result depends on the selected threshold.
 ** A-contrario: to be described

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 {{documentation/{{documentation/version}}/module-section|Module Description}}
-This module was developed to detect  epileptogenic focus candidates using SPECT images. A MRI image can also be used.
+In refractory epilepsy, the goal of neuroimaging is to localize the region of seizure onset. Tracers that accumulate and remain ﬁxed proportional to regional cerebral blood ﬂow (rCBF) at the time of injection are used to obtain SPECT images of the brain activity during and between seizures.
-Below you will find a description of the functionality of the module.
+This module was developed to detect  epileptogenic focus candidates using basal and ictal SPECT images. A MRI image can also be used.

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-This work is part of <br>
+This work was supported by Comision Sectorial de Investigacion Cientıfica (CSIC, Universidad de la Republica, Uruguay) under program "Proyecto de Inclusión Social".  <br>
 Author: Guillermo Carbajal, Álvaro Gómez, Universidad de la República, Uruguay<br>
 Contact: Guillermo Carbajal, <email>carbajal@fing.edu.uy</email><br>

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 Compare candidates obtained using SISCOM and a-contrario method.
-[[File:CompareDetections.png]]
+[[File:CompareDetections.png|Epileptogenic focus candidates]]
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 ** Differential method: Given two SPECT images (basal and ictal) in the same space (already registered), the images are substracted. An intensity normalization step is applied.
 ** A-contrario: to be described

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