<?xml version="1.0"?>
<feed xmlns="http://www.w3.org/2005/Atom" xml:lang="en">
	<id>https://www.slicer.org/w/index.php?action=history&amp;feed=atom&amp;title=Documentation%2F4.6%2FModules%2FBrainExtractionTool</id>
	<title>Documentation/4.6/Modules/BrainExtractionTool - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://www.slicer.org/w/index.php?action=history&amp;feed=atom&amp;title=Documentation%2F4.6%2FModules%2FBrainExtractionTool"/>
	<link rel="alternate" type="text/html" href="https://www.slicer.org/w/index.php?title=Documentation/4.6/Modules/BrainExtractionTool&amp;action=history"/>
	<updated>2026-04-17T04:48:24Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.33.0</generator>
	<entry>
		<id>https://www.slicer.org/w/index.php?title=Documentation/4.6/Modules/BrainExtractionTool&amp;diff=47873&amp;oldid=prev</id>
		<title>UpdateBot: Nightly -&gt; 4.6</title>
		<link rel="alternate" type="text/html" href="https://www.slicer.org/w/index.php?title=Documentation/4.6/Modules/BrainExtractionTool&amp;diff=47873&amp;oldid=prev"/>
		<updated>2016-11-07T07:42:44Z</updated>

		<summary type="html">&lt;p&gt;Nightly -&amp;gt; 4.6&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;lt;noinclude&amp;gt;{{documentation/versioncheck}}&amp;lt;/noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-header}}&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-section|Introduction and Acknowledgements}}&lt;br /&gt;
{{documentation/{{documentation/version}}/module-introduction-start|{{documentation/modulename}} }}&lt;br /&gt;
{{documentation/{{documentation/version}}/module-introduction-row}}&lt;br /&gt;
This work was partially funded by CAPES and CNPq (grant 201871/2015-7/SWE), a Brazilian research support agency. Information on CAPES can be obtained from the official websites, [http://www.capes.gov.br/ CAPES here] and [http://www.cnpq.br/ CAPES here].&amp;lt;br&amp;gt;&lt;br /&gt;
Author: Antonio Carlos da S. Senra Filho, CSIM Laboratory (University of Sao Paulo, Department of Computing and Mathematics)&amp;lt;br&amp;gt;&lt;br /&gt;
Contact: Antonio Carlos da S. Senra Filho &amp;lt;email&amp;gt;acsenrafilho@usp.br&amp;lt;/email&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-introduction-row}}&lt;br /&gt;
{{documentation/{{documentation/version}}/module-introduction-logo-gallery&lt;br /&gt;
|Image:CSIM-logo.png|CSIM Laboratory &lt;br /&gt;
|Image:USP-logo.png|University of Sao Paulo&lt;br /&gt;
|Image:CNPq-logo.png|CNPq Brazil&lt;br /&gt;
|Image:CAPES-logo.png|CAPES Brazil&lt;br /&gt;
}}&lt;br /&gt;
{{documentation/{{documentation/version}}/module-introduction-end}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-section|Module Description}}&lt;br /&gt;
{{documentation/{{documentation/version}}/module-description}}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
This module aims to extracted the brain in structural MRI images, namely T1 weighted MRI images. The method is based on the non-parametric algorithm proposed by Iglesias et. al. &amp;lt;ref&amp;gt; Iglesias, J.E. et al., 2011. &amp;quot;Robust Brain Extraction Across Datasets and Comparison With Publicly Available Methods&amp;quot;. IEEE Transactions on Medical Imaging, 30(9), pp.1617–1634&amp;lt;/ref&amp;gt;. The application with T2 and proton density MRI images were not intensively tested, but it is assumed that the algorithm is robust with those image contrasts as well.&lt;br /&gt;
&lt;br /&gt;
In addition, better results could be achieved if some pre processing steps are performed before calling the brain extraction module. I suggest the use of a noise filtering method and field inhomogeneity correction methods in advance. See the modules [[Documentation/{{documentation/version}}/Modules/AADImageFilter|AAD Image Filter]] and [[Documentation/{{documentation/version}}/Modules/N4ITKBiasFieldCorrection|N4 Bias Field Correction]] as some examples of useful modules for those image pre-processing steps.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-section|Use Cases}}&lt;br /&gt;
Most frequently used for these scenarios:&lt;br /&gt;
* Use Case 1: Initial image processing step for many neuroimage analysis, such as in DTI and cortical thickness estimation.&lt;br /&gt;
**It would be useful for tissue classication.&lt;br /&gt;
* Use Case 2: Information reduction to registration pipelines&lt;br /&gt;
**The non-brain tissues tend to decrease the quality of many registration algorithms.&lt;br /&gt;
* Use Case 3: Increase the precision of classification algorithms for neurodegenerative brain diseases diagnosis.&lt;br /&gt;
**Could offer a better segmentation and classification on specific brain image analysis such as in Multiple Sclerosis lesion segmentation as well as the global brain atrophy.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;gallery&amp;gt;&lt;br /&gt;
Image:AllHeadMRI.png|T1w MRI&lt;br /&gt;
Image:BrainMRI.png|Brain extracted T1 MRI&lt;br /&gt;
&amp;lt;/gallery&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-section|Tutorials}}&lt;br /&gt;
N/A&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-section|Panels and their use}}&lt;br /&gt;
[[Image:brainextractiontool_gui.png|thumb|380px|User Interface]]&lt;br /&gt;
*Input Volume:&lt;br /&gt;
**Insert an input scalar volume&lt;br /&gt;
*Output Volume:&lt;br /&gt;
**Set the output volume&lt;br /&gt;
*Binary Mask:&lt;br /&gt;
**Set the output binary mask, i.e. the label generated by the brain given in the output volume.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-section|Similar Modules}}&lt;br /&gt;
*[[Documentation/{{documentation/version}}/Modules/SkullStripper|Skull Stripper]]&lt;br /&gt;
*[[Documentation/{{documentation/version}}/Modules/SwissSkullStripper|Swiss Skull Stripper]]&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-section|References}}&lt;br /&gt;
* [http://dcm.ffclrp.usp.br/csim Computing in Signals and Images in Medicine Laboratory (CSIM)]&lt;br /&gt;
&lt;br /&gt;
Repositories:&lt;br /&gt;
* Source code: [https://github.com/CSIM-Toolkits/Slicer GitHub repository]&lt;br /&gt;
* Issue tracker:  [https://github.com/CSIM-Toolkits/Slicer/issues open issues and enhancement requests]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;br /&gt;
{{documentation/{{documentation/version}}/module-footer}}&lt;br /&gt;
[[Category:Documentation/{{documentation/version}}/Modules/Informatics]]&lt;br /&gt;
&amp;lt;!-- ---------------------------- --&amp;gt;&lt;/div&gt;</summary>
		<author><name>UpdateBot</name></author>
		
	</entry>
</feed>