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Tumor Ablation Therapy of Liver Cancers with an Open Magnetic Resonance Imaging-based Navigation System
Institution:
 1Department of Future Medicine and Innovative Medical Information, Faculty of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan, maedat@dem.med.kyushu-u.ac.jp.
2Redox Navi Institute, Kyushu University, Fukuoka, Japan
3Department of Advanced Medical Initiatives, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
Publisher:
 Surg Endosc
Publication Date:
 May-2009
Volume Number:
 23
Issue Number:
 5
Pages:
 1048-1053
Citation:
 Surg Endosc. 2009 May;23(5):1048-53.
PubMed ID:
 18813998
Keywords:
 Open MRI, Navigation, Ablation, Liver cancer
Appears in Collections:
SLICER, SNR
Generated Citation:
 Maeda T., Hong J., Konishi K., Nakatsuji T., Yasunaga T., Yamashita Y., Taketomi A., Kotoh K., Enjoji M., Nakashima H., Tanoue K., Maehara Y., Hashizume M. Tumor Ablation Therapy of Liver Cancers with an Open Magnetic Resonance Imaging-based Navigation System. Surg Endosc. 2009 May;23(5):1048-53. PMID: 18813998.
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As minimally invasive treatments for liver cancers, percutaneous ablation therapies represent a valid alternative to liver resections, especially in patients with poor liver function. Recently, image-guided surgical and interventional procedures using open magnetic resonance imaging (MRI) have been introduced. METHODS: We performed percutaneous ablation therapy for 51 nodules of liver cancer in 34 patients using a navigation system based on open MRI. During the ablation therapy, the ultrasonography (US) probe, needle, and tumor were displayed on the MR image. Immediately after the procedure, the therapeutic effect was evaluated by open MRI. RESULTS: In all cases, percutaneous puncture into the tumors was successful, even in the case of tumor undetectable by US. Mean fiducial registration error was approximately 3 mm. MR images captured after the procedure clearly demonstrated the ablated area. No mortality or major complications occurred, except for mild hemorrhage, pyrexia, and ascites. CONCLUSIONS: We developed a novel navigation system integrating US and MR images using open MRI for percutaneous ablation therapy of liver cancers. The presented system allows a safe and accurate approach to liver cancers, especially certain tumors that cannot be adequately visualized by US, and an evaluation of therapeutic results immediately after the procedures.

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