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Figure 7:Top row: qualitative comparison of the automatic segmentation results obtained using different atlases. The differences are mostly localized to subcortical GM. Bottom row: GM/WM/CSF segmentation for the R1 region used in the evaluation. Note inconsistencies in CSF segmentation by the raters.
Figure 7:Top row: qualitative comparison of the automatic segmentation results obtained using different atlases. The differences are mostly localized to subcortical GM. Bottom row: GM/WM/CSF segmentation for the R1 region used in the evaluation. Note inconsistencies in CSF segmentation by the raters.
Figure 2: Three-dimensional models of TBI anatomy for Patient 1 (acute baseline time point), as generated in 3D Slicer. Each row displays one of six canonical views of the brain, whereas each column corresponds to a structure type (ventricles, non-hemorrhagic lesions, hemorrhagic lesions, and full model). In (A), ventricles are shown as opaque, whereas extracerebral injuries, gray matter (GM) and white matter (WM) volumes are shown as transparent to facilitate visualization of each structure in relationship to cortical landmarks. In (B–D), ventricles are also shown as transparent for similar reasons. Arrows indicate TBI-related pathology of interest (see text for elaboration).
Figure 2: Three-dimensional models of TBI anatomy for Patient 1 (acute baseline time point), as generated in 3D Slicer. Each row displays one of six canonical views of the brain, whereas each column corresponds to a structure type (ventricles, non-hemorrhagic lesions, hemorrhagic lesions, and full model). In (A), ventricles are shown as opaque, whereas extracerebral injuries, gray matter (GM) and white matter (WM) volumes are shown as transparent to facilitate visualization of each structure in relationship to cortical landmarks. In (B–D), ventricles are also shown as transparent for similar reasons. Arrows indicate TBI-related pathology of interest (see text for elaboration).
Figure 1: Pre- and postoperative (two years after tracheoplasty) images. (a, b) Endoscopic pictures. (c, d) Median sagittal computed tomography reconstruction (three-dimensional Slicer software, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA). Stars show the site of the grafts.
Figure 1: Pre- and postoperative (two years after tracheoplasty) images. (a, b) Endoscopic pictures. (c, d) Median sagittal computed tomography reconstruction (three-dimensional Slicer software, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA). Stars show the site of the grafts.
Figure 1: Volumetric brain tumor mapping of FLAIR, Necrosis, and Contrast Enhancement. A 55 year old male patient with a right temporal GBM. (a) Axial FLAIR image demonstrates segmentation (in blue) of the region of FLAIR hyperintensity corresponding to the area of edema/ tumor infiltration. Notice the segmented enhancement (yellow) and necrosis (orange) that has been segmented on the T1WI post- contrast. (b) The segmented edema/tumor infiltration (blue), enhancement (yellow) and necrosis (orange) are seen overlaid on a base post- contrast T1WI. (c) Axial post-contrast enhanced T1WI demonstrates the segmentation of the enhancement (yellow) and necrosis (orange).
Figure 1: Volumetric brain tumor mapping of FLAIR, Necrosis, and Contrast Enhancement. A 55 year old male patient with a right temporal GBM. (a) Axial FLAIR image demonstrates segmentation (in blue) of the region of FLAIR hyperintensity corresponding to the area of edema/ tumor infiltration. Notice the segmented enhancement (yellow) and necrosis (orange) that has been segmented on the T1WI post- contrast. (b) The segmented edema/tumor infiltration (blue), enhancement (yellow) and necrosis (orange) are seen overlaid on a base post- contrast T1WI. (c) Axial post-contrast enhanced T1WI demonstrates the segmentation of the enhancement (yellow) and necrosis (orange).
Figure 6b: Segmented model of the LA, RA, PV and septal wall, with the colour map representing the GII at different locations. Red represents points with low GII, while blue represents points with high GII
Figure 6b: Segmented model of the LA, RA, PV and septal wall, with the colour map representing the GII at different locations. Red represents points with low GII, while blue represents points with high GII
Figure 1: Whole-brain segmentation. The figure shows the segmentation results from the average brain of Sample 2. The three-dimensional renderings illustrate the shape, extension, and relative position within the brain of the different neuroanatomical structures.
Figure 1: Whole-brain segmentation. The figure shows the segmentation results from the average brain of Sample 2. The three-dimensional renderings illustrate the shape, extension, and relative position within the brain of the different neuroanatomical structures.
Figure 2: Distribution and frequency of WMHs in the normal (A), intermediate (B), and impaired (C) mobility groups. WMH frequency maps are overlaid on the corresponding anatomical slice of the ICBM atlas. WMH frequency is color-coded in percent (color bar). Panel D shows a 3D model reconstruction of the most affected structure, the corona radiata (green), within the white matter (transparent gray), and with ventricles (blue) also shown.
Figure 2: Distribution and frequency of WMHs in the normal (A), intermediate (B), and impaired (C) mobility groups. WMH frequency maps are overlaid on the corresponding anatomical slice of the ICBM atlas. WMH frequency is color-coded in percent (color bar). Panel D shows a 3D model reconstruction of the most affected structure, the corona radiata (green), within the white matter (transparent gray), and with ventricles (blue) also shown.
Figure 3: Extraction of the visual fibers of the corpus callosum with DTI tractography. A region-of-interest was first manually drawn in the splenium of the corpus callosum, on the midsagittal slice of each participants' Fractional Anisotropy image (panel a). Panel d shows the extracted visual corpus fibers for three representative individuals.
Figure 3: Extraction of the visual fibers of the corpus callosum with DTI tractography. A region-of-interest was first manually drawn in the splenium of the corpus callosum, on the midsagittal slice of each participants' Fractional Anisotropy image (panel a). Panel d shows the extracted visual corpus fibers for three representative individuals.
Figure 3: Images shown in the 3D Slicer using the intraoperative tractography navigation software module. The light green volume delineates the tumor location, the orange sphere represents the seed fiducial that is located at the tracked surgical tool tip location, the yellow regions indicate eloquent cortex as shown by language task-associated functional magnetic resonance imaging, and the tubular fibers represent the white matter tracts seeded by the fiducial location. White matter tracts are color coded according to their fractional anisotropy (color scale). A, white matter fibers being seeded by a fiducial representing tool tip position. Some infiltrating fibers can be seen within the segmented tumor volume (arrows). B, intraoperative querying of tractography data sets using the tool offset function. Fiducials F1 and F2 represent the surgical tool tip location and a fixed geometric offset respectively. The navigation module allows for geometric offsets from 280 to 80 mm from the tool tip position. The 2 fiducials can seed the tractography data set simultaneously.
Figure 3: Images shown in the 3D Slicer using the intraoperative tractography navigation software module. The light green volume delineates the tumor location, the orange sphere represents the seed fiducial that is located at the tracked surgical tool tip location, the yellow regions indicate eloquent cortex as shown by language task-associated functional magnetic resonance imaging, and the tubular fibers represent the white matter tracts seeded by the fiducial location. White matter tracts are color coded according to their fractional anisotropy (color scale). A, white matter fibers being seeded by a fiducial representing tool tip position. Some infiltrating fibers can be seen within the segmented tumor volume (arrows). B, intraoperative querying of tractography data sets using the tool offset function. Fiducials F1 and F2 represent the surgical tool tip location and a fixed geometric offset respectively. The navigation module allows for geometric offsets from 280 to 80 mm from the tool tip position. The 2 fiducials can seed the tractography data set simultaneously.
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